PJH Studios

Tag: neuroscience

  • Sleep is a spectrum

    We’ve known that sleep has cycles, but more research is showing that how we sleep is more nuanced and may exist as a spectrum.

    It’s still largely mysterious how the brain manages to move between these states safely and efficiently. But studies targeting transitions both into and out of sleep are starting to unravel the neurobiological underpinnings of these in-between states, yielding an understanding that could explain how sleep disorders, such as insomnia or sleep paralysis, can result when things go awry.

    Sleep has been traditionally thought of as an all-or-nothing phenomenon, Lewis said. You’re either awake or asleep. But the new findings are showing that it’s “much more of a spectrum than it is a category.”

  • Making music after death

    Popular Mechanics with an interesting art installation involving posthumous brain matter to make music.

    American composer Alvin Lucier was well-known for his experimental works that tested the boundaries of music and art. A longtime professor at Wesleyan University (before retiring in 2011), Alvin passed away in 2021 at the age of 90. However, that wasn’t the end of his lifelong musical odyssey.

    Earlier this month, at the Art Gallery of Western Australia, a new art installation titled Revivification used Lucier’s “brain matter”—hooked up to an electrode mesh connected to twenty large brass plates—to create electrical signals that triggered a mallet to strike the varying plates, creating a kind of post-mortem musical piece. Conceptualized in collaboration with Lucier himself before his death, the artists solicited the help of researchers from Harvard Medical School, who grew a mini-brain from Lucier’s white blood cells. The team created stem cells from these white blood cells, and due to their pluripotency, the cells developed into cerebral organoids somewhat similar to developing human brains.

  • The brain washes itself during sleep

    Scientists uncover how the brain washes itself during sleep.

    Scientists think sleep is the brain’s rinse cycle, when fluid percolating through the organ flushes out chemical waste that accumulated while we were awake. But what propels this circulation has been uncertain. A study of mice, reported today in Cell, suggests regular contractions of blood vessels in the brain, stimulated by the periodic release of a chemical cousin of adrenaline, push the fluid along.